This research, which held out the promise of potentially creating the worlds second cancer vaccine, was of such fundamental importance that it led to zur hausen winning the nobel. Harald zur hausen 1936 was awarded a share of the 2008 nobel prize in physiology or medicine for discovering that papillomaviruses cause cervical cancer. Harald zur hausen by using hausens research, a vaccine was eventually developed a vaccine. German virologist harald zur hausen was convinced by the early 1970s that the skin wart virus, human papilloma, was implicated in cervical cancer. Prof harald zur hausen, a 2008 nobel laureate for medicine at the german cancer research centre, will visit ho chi minh city as a keynote speaker in the 4th asean event series bridgesdialogues. Harald zur hausen is awarded the nobel medicine prize. Although harald zur hausen was affiliated with penn only for a short period of time, he still is, and we have reliable sources for this fact, see his cv and this notice page 4.
Following a role model in science maastricht university. Born in gelsenkirchenbuer in germany on march 11th, 1936, professor harald zur hausen, emeritus professor of virology at the university of. The studies of zur hausen on oncogenic viruses submitted a finding that chronic infection with certain highly invasive human papilloma viruses hpv16 and hpv18 types causes cervix. Pdf structural analysis of a replication protein encoded. Regulation of minute virus of mice ns1 replicative. Mathematik g09 klassenarbeit i aufgabe 1 2 3 4 5 6 7 punkte max 6 2 2 4 2 4 2 punkte 1 berechne 629. The hpv genome has been largely decoded, and the mechanisms of its ability to cause malignant transformation of host cell lines are becoming understood. Through years of research, zur hausen, with the help of the hela cell line, discovered the link between human papillomavirus and cervicla cancer. Harald zur hausen by using hausen s research, a vaccine was eventually developed a vaccine. With the majority of hpv cases being found in poorer, less developed countries, hausen was appaled. This new edition of the wellreceived introduction to solidstate physics provides a comprehensive overview of the basic theoretical and experimental concepts. Structural analysis of a replication protein encoded by a plasmid isolated from a multiple sclerosis patient turgay kilic, a, b alexander n. This research, which held out the promise of potentially creating the worlds second cancer. Iucr structural analysis of a replication protein encoded.
In the early 1980s a german virologist named harald zur hausen identified the human papillomavirus hpv as the cause of up to 75% of all cases of cervical cancers. The discovery led to a nobel prize for harald zur hausen in 2008. Shouldnt this list include all nobel laureates affiliated with the university of pennsylvania, not only those acknowledged on an official and outdated summary page. The president asked the general assembly for a motion to approve the accounts. Harald zur hausens experiments on human papillomavirus. Harald zur hausens experiments on human papillomavirus causing cervical cancer 19761987from 1977 to 1987, harald zur hausen led a team of researchers across several institutions in germany to investigate whether the human papillomavirus hpv caused cervical cancer. A specific class of infectious agents isolated from bovine. Jun 19, 2015 harald zur hausen 1936 was awarded a share of the 2008 nobel prize in physiology or medicine for discovering that papillomaviruses cause cervical cancer. Paediatric virology as a new educational initiative. With this, he developed a vaccine that is given primarily given to. Eduard zur hausen, the youngest son of a farmer in the german city of gelsenkirchenbuer in. Harald zur hausen, papillomaviruses, and cervical cancer. Loeb the joseph gottstein memorial cancer research laboratory, department of pathology, university of washington, seattle, washington 98i95 in this paper i will consider an aspect of carcinogenesis that. Larson phd, seth mnookin, in the vaccine book second edition, 2016.
Whether youve loved the book or not, if you give your honest and detailed thoughts then people will find new books that are right for them. Its probably no coincidence that all three of haralds children have phds, although not all in virology like axel. In the 1970s, harald zur hausen detected the human papillomavirus hpv in warts and cervical cancer, and he subsequently isolated and cloned different strains of hpv. Evidence on the interaction of information and social comparisons, and also for behavioral implications, is. Harald zur hausen 1936 the embryo project encyclopedia. Harald zur hausen born 11 march 1936 in gelsenkirchen is a german virologist and professor emeritus. While individuals are commonly exposed to uncertainty, to date, few empirical studies addressed social comparisons in an uncertain enviroment. Harald zur hausen simple english wikipedia, the free. Harald zur hausen, german virologist who was a corecipient, with fran. University of freiburg faculty of medicine wikipedia. Two basic scientists walk into a translational space. Pdf history of discoveries and pathogenicity of tt viruses.
Hpve7 oncoproteins as new markers for detection of cervical. This was in the beginning of 1983, and harald came and gave this big lecture. Partial characterization of viral dna from human genital warts. He won the nobel prize in physiology or medicine in 2008 for his discoveries on the role of papilloma viruses which he shared with luc montagnier and francoise barresinoussi. He found dna to be a family of viruses of which only some hpv types particularly type 16 and 18 cause cancer. Cancer under the editorship of dr harald zur hausen. Cancer research 49, 54895496, october 15, 1989 special lecture endogenous carcinogenesis. Harald zur hausen, nobel prize laureate for physiology or medicine 2008, at a press conference at the karolinska in solna deutsch. Our ability to transplant genes from one human second meeting, human dna tumor viruses, was organized cell to another, or from a human cell to an animal cell deficient by harald zur hausen. Harald zur hausen, born march 11, 1936, gelsenkirchen, germany, german virologist who was a corecipient, with fran.
Harald zur hausen date of birth march 11, 1936 place of birth gelsenkirchen, germany marital state married with dr. Sa incercam sa rezumam ideile acestui memorabildiscurs, subliniind ca franta este. Molecular oncology into the twentyfirst centurypresidential address1 lawrence a. Harald zur hausen won the prestigious nobel prize in 2008 for his research on the role of the human papillomavirus in cervical cancer, which led to the development of a vaccine for teenage girls. Thirty years later we stand on the threshold of a vaccine to prevent this major killer of women. Professor harald zur hausen, nobel prize laureate in physiology or medicine, for the mission on cancer mr pascal lamy, former trade commissioner and directorgeneral of the world trade organisation, for the mission on healthy oceans, seas, coastal and inland waters. Popov, c amelie burkkorner, d, e anna koromyslova, a, b harald zur hausen, d timo bund d and grant s. International union against cancer meeting of the uicc.
The profile of harald zur hausen, german virologist and nobelprize winner for medicine in 2008, is presented in the context of his life and scientific achievements. Nobel prize for medicine awarded to harald zur hausen. Zur hausen was given half the award in recognition of his discovery of the human papilloma virus hpv and its link to cervical cancer zur hausen received an m. Patterns and trends in semantic predications springerlink. Harald zur hausen went against existing dogmas and discovered that human papilloma virus hpv causes cervical cancer, the second most common cancer among women in the caribbean. The faculty was founded in 1457 as one of germanys oldest and is regarded among its most distinguished. Hpve7 oncoproteins as new markers for detection of. Minute virus of mice mvm, an autonomous parvovirus, is a small nonenveloped spherical particle containing singlestranded linear dna. Nov 28, 2017 a distinct advantage of a graph database over the traditional relational database is a reduced complexity of queries. Pdf structural analysis of a replication protein encoded by. Since uses different arguments than, i created a family of templates based on sidebar, but modified so most arguments named the same as navbox. He received the award jointly with luc montagnier and francoise barresinoussi, who were given their portion for discovering hiv 1. List of nobel laureates affiliated with the university.
His research concluded that patients infected with hpv types 16 and 18 were at an increased risk of developing cancer. He drew the assemblys attention to the level of the unrestricted reserves equivalent to five months of operating costs stating than in his view uicc should have a least a years operating costs in reserve. Other readers will always be interested in your opinion of the books youve read. A distinct advantage of a graph database over the traditional relational database is a reduced complexity of queries. Social comparisons under uncertainty in public finance. It seems to be difficult to combine the possible link between animal farming and hematopoietic malignancies with the. A read is counted each time someone views a publication summary such as the title, abstract, and list of authors, clicks on a figure, or views or downloads the fulltext.
200 647 1430 1425 588 1195 836 321 94 1232 24 44 32 1 1407 899 628 673 1063 316 911 6 240 556 1376 1305 284 554 386 362 918 946 123 1307 443